The eastern white cedar is a typical species of calcareous or slightly acidic soils, but it can tolerate both dry and wet conditions. It grows in swamps, bogs, and along streams and rivers, and can even take root in cracks or on rocky cliffs.
This tree is common in mixed and boreal forests, though it does not tolerate prolonged drought. It thrives in partial shade or diffused light.
In North America, the eastern white cedar is found in the northeastern and midwestern United States (Maine, Vermont, New Hampshire, New York, Michigan, Wisconsin, Minnesota). In Canada, it grows across much of the country except the Northwest Territories, Ungava, Yukon, Alberta, and Newfoundland.